Low and Intermediate Toxicity Drug Compounds

Handling procedures for low and intermediate toxicity drug compounds are much less controlled than those of a potent nature, largely because their pharmacological effects, if exposed to, are less severe. Typically substances of this nature will have pharmacological effects when used in concentrations over 10mg/Kg. Low and intermediate toxicity drug...

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Categorisation of Drug Compounds

The basis of the categorisation of drug compounds is inherent to their toxicity.  Drug entities are initially classified in terms of their respective toxicity and potency characteristics. Toxicity can be determined in various ways, such as through observations in pre-clinical toxicological investigations and in clinical trials. Other factors are: Mechanism...

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