Chemical Criteria By Drug Category

The following table shows the chemical criteria by drug category. It uses the varying properties of drugs and places them in their respective category: Low Toxicity (1), Intermediate Toxicity (2), Potent (3) or Highly Potent (4). This table is useful in determining the types of Safety and Engineering controls that need to be put in...

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Low and Intermediate Toxicity Drug Compounds

Handling procedures for low and intermediate toxicity drug compounds are much less controlled than those of a potent nature, largely because their pharmacological effects, if exposed to, are less severe. Typically substances of this nature will have pharmacological effects when used in concentrations over 10mg/Kg. Low and intermediate toxicity drug...

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Categorisation of Drug Compounds

The basis of the categorisation of drug compounds is inherent to their toxicity.  Drug entities are initially classified in terms of their respective toxicity and potency characteristics. Toxicity can be determined in various ways, such as through observations in pre-clinical toxicological investigations and in clinical trials. Other factors are: Mechanism...

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Exposure Potential to Drug Compounds in the Laboratory

Technological advances in drug research and development provide us with increasingly effective medicines that can be taken in correspondingly lower doses, yet still achieving longer term medicinal effects. While these advancements are of obvious benefit to patients, as they will receive fewer treatments with the added advantage of longer term...