Local Exhaust Ventilation Controls for Pharmaceutical Laboratories

General Guidance for Local Exhaust Ventilation Controls: Providing effective extraction and filtration for localized containment systems. Each laboratory should be equipped with enough fume cupboards and ventilated enclosures for the work anticipated. Fume cupboards should be connected to a high volume, low static, mechanical exhaust system. Emission control or stack...

Safety Design Aspects of Pharmaceutical Laboratories

Safety Design Aspects of Pharmaceutical Laboratories.The safe handling of potent compounds within a laboratory environment can be best accomplished by adopting a containment strategy which addresses two defined areas of control:The building design, which includes the air handling facilities and built in control measures such as airlocks, laboratory layout and...

Low and Intermediate Toxicity Drug Compounds

Handling procedures for low and intermediate toxicity drug compounds are much less controlled than those of a potent nature, largely because their pharmacological effects, if exposed to, are less severe. Typically substances of this nature will have pharmacological effects when used in concentrations over 10mg/Kg. Low and intermediate toxicity drug...

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Categorisation of Drug Compounds

The basis of the categorisation of drug compounds is inherent to their toxicity.  Drug entities are initially classified in terms of their respective toxicity and potency characteristics. Toxicity can be determined in various ways, such as through observations in pre-clinical toxicological investigations and in clinical trials. Other factors are: Mechanism...

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